The world is gaining knowledge about our brains…
For a more complete list. please visit: https://www.braingate.org/publications/
1. An Accurate and Rapidly Calibrating Speech Neuroprosthesis
Card NS, Wairagkar M, Iacobacci C, et al. New England Journal of Medicine (2024); 391(7):609–618.
https://www.nejm.org/doi/full/10.1056/NEJMoa2314132
2. An Instantaneous Voice-Synthesis Neuroprosthesis
Wairagkar M, Iacobacci C, Card NS, et al. Nature (2025).
https://www.nature.com/articles/s41586-025-09127-3
3. Inner Speech in Motor Cortex and Implications for Speech Neuroprostheses
Kunz EM, Card NS, Iacobacci C, et al. Cell (2025).
https://www.cell.com/cell/fulltext/S0092-8674(25)00681-6
4. Speech Motor Cortex Enables BCI Cursor Control and Click
Card NS, Wairagkar M, Iacobacci C, et al. Journal of Neural Engineering (2025).
https://pmc.ncbi.nlm.nih.gov/articles/PMC12208300/
5. Error Encoding in Human Speech Motor Cortex
(BrainGate2 participants T15 and T12). Published 2025.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12259010/
6. Long-Term Independent Use of an Intracortical Brain-Computer Interface for Speech and Cursor Control
(Preprint, bioRxiv, 2025.)
https://www.biorxiv.org/content/10.1101/2025.06.26.661591v1.full
7. Long-Term Performance of Intracortical Microelectrode Arrays in 14 BrainGate Clinical Trial Participants
(Preprint/medRxiv, 2025.)
https://www.medrxiv.org/content/10.1101/2025.07.02.25330310v1
8. Cross-Brain Transfer of High-Performance Intracortical Speech and Handwriting BCIs
(Preprint, bioRxiv, January 2026. Participants include T15.)
https://www.biorxiv.org/content/10.64898/2026.01.12.699110v1
9. Cross-Subject Decoding of Human Neural Data for Speech Brain-Computer Interfaces
(Preprint, bioRxiv, February 2026. Uses T15/Card dataset.)
https://www.biorxiv.org/content/10.64898/2026.02.27.708564v1
10. Long-term independent use of an intracortical brain–computer interface for speech and cursor control
Card, N.S., Singer-Clark, T., Peracha, H. et al. Nat Med 32, 2504–2510 (2026).
https://www.nature.com/articles/s41591-026-04414-6
11. At-home brain implant gives man with motor neuron disease his daily life back
Nature 654, 849-850 (2026)
Over the past few years, the researchers from the amazing Braingate team, working on Casey’s BCI have received a cascade of major awards based on the work they were able to do with Casey:
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In 2023, the research team won first place at the BCI Awards, an international competition that highlights the most innovative and impactful advances in brain-computer interface technology. If you’re a nerd, you can actually watch the video where the researchers explain how the BCI works – starring Casey, of course.
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In 2025, pioneering researcher Dr. Maiyatree Wairagkar received the Peter and Patricia Gruber International Research Award in Neuroscience for her work on the BCI in Casey’s brain. The Gruber Award is internationally prestigious and recognizes research that fundamentally reshapes how we understand the brain and its ability to interface with technology.
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Also in 2025, neurosurgeon David Brandman and his team at the UC Davis Neuroprosthetics Lab were awarded the very prestigious Herbert Pardes Clinical Research Excellence Award for this work. This award is reserved for clinical research that doesn’t just advance knowledge, but changes patient care. Casey’s BCI is already shaping how clinicians think about restoring communication and autonomy to people with severe paralysis.
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Finally, in 2025, Nicholas Card, the lead author on Casey’s BCI study from the UC Davis Department of Neurological Surgery, was awarded one of the highly competitiveCareer Awards at the Scientific Interface by the Burroughs Wellcome Fund. This funding is an investment in the long-term future of the field, and it is directly tied to the success and promise of the work being done with Casey.
Each award signals that this work is pushing the boundaries of what’s possible for enabling speech for people with paralysis – such as people with ALS.
Because of conflict-of-interest and research ethics rules, Casey cannot personally receive financial benefits from any of them.
Even when an award is directly tied to work done in his brain - work that requires thousands of hours of effort, patience, and physical risk - the money can only go to institutions and researchers, never to the person making the breakthrough possible.
The science moves forward. Careers advance. Institutions are rewarded. And the person whose body is doing the work still has to fundraise to stay alive.
That’s why #TeamCasey continues to fundraise at our GoFundMe: “Save Casey Harrell and his extraordinary brain.” Casey and his family need support to sustain Casey’s well-being, as ALS care is astronomically expensive.
We are fighting to keep Casey and his extraordinary brain alive - for his family and friends, for the environmental movement he has helped lead, and for the advancement of research to give voice to millions of people who desperately need this technology themselves.
We can make sure that this person we love, who is helping move science forward, is not left behind by it. Please support Casey by making a donation at the GoFundMe.